{"id":70891,"date":"2023-03-17T12:32:46","date_gmt":"2023-03-17T16:32:46","guid":{"rendered":"https:\/\/hitconsultant.net\/?p=70891"},"modified":"2023-03-17T12:32:49","modified_gmt":"2023-03-17T16:32:49","slug":"study-mrna-boosters-extend-covid-19-protection","status":"publish","type":"post","link":"https:\/\/hitconsultant.net\/2023\/03\/17\/study-mrna-boosters-extend-covid-19-protection\/","title":{"rendered":"Study Confirms mRNA Boosters Extend COVID-19 Protection but Wane Over Time"},"content":{"rendered":"\n
\"\"<\/figure>\n\n\n\n

What You Should Know:<\/strong><\/p>\n\n\n\n

– A nationwide U.S. study of more than 893,000 adults provides solid evidence confirming that mRNA booster immunizations extend protection against moderate and severe COVID for four to five months. <\/p>\n\n\n\n

– These findings, published in The BMJ<\/em>, provide a more complete understanding of the effectiveness and durability of third and fourth doses of the mRNA vaccines, informing policymakers and providing individuals with confirmation of the importance and value of boosters.<\/p>\n\n\n\n

Evidence-Based Research Supports the Need For Additional Boosters<\/strong><\/p>\n\n\n\n

Vaccine effectiveness provided by boosters waned less against severe disease than against moderate disease in all age groups according to the new study which was conducted by the Centers for Disease Control and Prevention\u2019s (CDC) VISION Network.<\/p>\n\n\n\n

\u201cWhile there have been recommendations for booster shots for a while until now we haven\u2019t had strong evidence of their effectiveness and how long that effectiveness lasts,\u201d said study co-author Brian Dixon, Ph.D., of the Regenstrief Institute and Indiana University Richard M. Fairbanks School of Public Health. \u201cIn our new study, we looked at tens of thousands of patients in multiple states, seen over a year and a half. Our analysis provides compelling evidence, both of the effectiveness of boosting to increase immunity, and that this immunity begins to wane after four or five months, indicating additional booster doses are necessary.<\/p>\n\n\n\n

\u201cThe recommendations to get boosted that were issued by the CDC months ago, were, in fact, the right recommendations,\u201d said Dr. Dixon. \u201cBooster doses are necessary to maintain a high level of immunity to severe COVID.\u201d<\/p>\n\n\n\n

The bivalent booster, available since early September 2022, targets both historic strains of the SARS-CoV-2 virus and the Omicron variants (BA.4 and BA.5) currently circulating in the U.S. and globally. he authors found that in the Omicron period mRNA vaccine protection against severe COVID-19 was initially high (89 percent) but waned after primary vaccination. Focusing on the durability of boosters against hospitalization, (i.e., severe disease), the study found that effectiveness increased markedly after a booster shot, waning again about four to five months after the booster. Protection increased again following a second booster. The protection and waning pattern with Moderna and Pfizer boosters were similar.<\/p>\n\n\n\n

\u201cIf it has been four months or longer since your last COVID booster, or if you had the initial two shots and have never received a booster, you should strongly consider a bivalent booster, which targets ancestral strains of the COVID virus plus subvariants Omicron BA.4 and BA.5,\u201d said study co-author Shaun Grannis, M.D., M.S., Regenstrief Institute Vice President for Data and Analytics. \u201cThe evidence that boosters can keep you healthy is compelling. Combining a COVID booster with an annual flu shot will help you make it through the respiratory disease season.\u201d\u00a0Dr. Grannis also is a professor of family medicine at IU School of Medicine.<\/p>\n\n\n\n

The BMJ study authors estimate that booster shots to counteract waning could prevent 300 hospitalizations in the U.S. for severe COVID per week.<\/p>\n\n\n\n

They note that the strengths of their new study include the \u201cnumber and diversity of sites and inclusion of outcomes of varying severity as well as a sample size large enough to detect modest waning of vaccine protection.\u201d Cases were compared with controls tested during the same week in the same geographic area, allowing the researchers to distinguish differences in vaccine effectiveness attributable to the waning of vaccine-induced immunity from those attributable to the ebb and flow of variants.<\/p>\n","protected":false},"excerpt":{"rendered":"

What You Should Know: – A nationwide U.S. study of more than 893,000 adults provides solid evidence confirming that mRNA booster immunizations extend protection against moderate and severe COVID for four to five months.  – These findings, published in The BMJ, provide a more complete understanding of the effectiveness and durability of third and fourth doses … Read More<\/a><\/p>\n","protected":false},"author":94,"featured_media":70892,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_genesis_hide_title":false,"_genesis_hide_breadcrumbs":false,"_genesis_hide_singular_image":false,"_genesis_hide_footer_widgets":false,"_genesis_custom_body_class":"","_genesis_custom_post_class":"","_genesis_layout":""},"categories":[25444],"tags":[44643],"yoast_head":"\nStudy Confirms mRNA Boosters Extend COVID-19 Protection but Wane Over Time<\/title>\n<meta name=\"description\" content=\"Studies confirm that mRNA booster immunizations extend 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